LABORATORY OF MOLECULAR GENETICS AND GENOMICS

The main purpose: Enhancing the crop resilience and plasticity to biotic and abiotic stress factors through understanding the genetic and physiological mechanisms of complex plant characteristics based on the use of state-of-the-art DNA technologies

Objective
Feature

ACHIEVEMENT

ESTABLISHING "SPEED BREEDING"
PLATFORM AT ZHETYSY UNIVERSITY
We became pioneers in Central Asia and in Kazakhstan by launching a «SPEED BREEDING» platform for accelerated selection of agricultural crops, which allows for up to 6 generations per year. Our laboratory played a key role in developing specialized protocols that significantly increase the speed of selection processes and research. These protocols accelerate the creation of improved crop varieties, ensuring faster development of high-yielding and resilient crops. We successfully harvested the first crop on this platform, marking an important milestone in the implementation of our project.
ONGOING GRANTS
Title: Adding values to the Central Asian wheat through the means of whole genome scanning, automated phenotyping and intensive selection
Goal: Identifying and harnessing the genomic variations that are related to significant economic traits and can dissect the founder effect in CAWP through modern tools of genomics and phenomics to strengthen wheat breeding practices in Kazakhstan.
ONGOING GRANTS
Workpackage for the accelerated breeding of  wheat and barley varieties within BR24992903 “Practical implementation of modern molecular-genetic, physiological-biochemical, biotechnological methods, and digital phenotyping in the breeding of economically significant agricultural crops” for 2024-2026 under budget program 217 “Science Development,” subprogram 101 “Program-targeted funding of scientific and/or scientific-technical activity entities.”
ONGOING GRANTS
KASP genotyping work package within the "Breeding and genetic technology for developing systems of long-term conservation, restoration, monitoring, and rational use of agrobiodiversity as a fundamental basis for improving breeding in the Republic of Kazakhstan."
GRANTS
Title: The development of new genetic resources for Kazakh bread wheat improvement
Goal: The aim of this grant proposal is to use such a genetic strategy to develop four bi-parental wheat populations, through crossing the Kazakh and UK commercial wheat varieties, and constructing their high-density genetic maps.
GRANTS
Title: The study of genetic control of adaptation and productivity of wheat
Goal: The study of genes controlling plant height as a component of adaptation and wheat yield
THE PASSAGE OF THE
INTERNATIONAL SCIENTIFIC CONFERENCE
The International Conference ICPBB 2024 was timed to coincide with the 30th anniversary of the founding of the “Institute of Plant Biology and Biotechnology”.
More than 200 scientists from 15 countries participated in the conference. During the conference two thematic workshops were organized: 
1. Biodiversity of wild flora of Central Asia.
2. OXFORD NANOPORE SEQUENCING: New Opportunities for Plant Genomics and Phytopathology (jointly with TechPrime LLP (Kazakhstan)).

Dr. Kanat Yermekbayev, Head of the Laboratory of Molecular Genetics and Genomics and junior researcher Adeliya Khamitova, as well as leading domestic and foreign scientists in the fields of genetics, genomics, breeding, physiology, biochemistry, and plant biotechnology, made plenary and oral presentations at the conference. Dr. Kanat Yermekbayev presented on "Breaking the founder effect controlling plant height in the Kazakh wheat gene pool"  within the framework of the project AP23488859 "Adding Value to the Central Asian Wheat through the Means of Whole Genome Scanning, Automated Phenotyping, and Intensive Selection." Junior researcher Adeliya Khamitova presented on "Four mapping populations and their genetic maps provided insights into the genetics of adaptation for Kazakhstani wheat germplasm" within the framework of the project  AP15473186 “The development of new genetic resources for Kazakh bread wheat improvement”. Opportunities for the development of breeding and genetic research using new genomic and phenomic technologies were discussed.

Young scientists of the laboratory of Molecular Genetics and Genomics, who participated in this forum, gained invaluable experience through listening to lectures of leaders of modern science, in the presentation of the results of their own work, in the discussion of pressing problems of plant biotechnology. PhD student of the 2nd year Sartbaeva Zhuldyz took the second place, as well as junior researcher Abduakassov Aibek took the third place for poster presentations among young scientists from more than 15 countries of the world.
 
THE PASSAGE OF THE
INTERNATIONAL SCIENTIFIC CONFERENCE
 "THE 8th ASIA-PACIFIC CHROMOSOME COLLOQUIUM" (APCC8).
Goal: From 17th to 25th September, 2023y, a scientific conference was held in the city of Tekirdağ (Turkey), Namık Kemal Üniversitesi and the main goal was the exchange of scientific information in the field of modern cytogenetics.
The program covered a wide range of research and topics in the field of chromosomal science and cytogenetics such as:
- Application of cytogenetics in medicine and agriculture;
- Chromosomal engineering;
- Cell cycle and division;
- B-chromosomes;
- Chromosomal aberrations;
- Genome structure and epigenetics and many other aspects.
Members of the research group of our university, project manager AP15473186 "Development of new genetic resources for the improvement of Kazakh wheat" Head of the laboratories of Molecular Genetics and Genomics Ermekbayev Kanat and junior researcher of the laboratories of Molecular Genetics and Genomics Sartbayeva Zhuldyz  took part in this scientific conference. The project executor, PhD student of the 2nd year Sartbayeva Zhuldyz took the third place in poster reports among more than 13 countries of the world in various categories of cytogenetics.
Learn more about the program of the international The symposium "8th Asia-Pacific Chromosome Colloquium (APCC8)" is available on the official website of the event: http://apcc2023.nku.edu.tr/
EVENTS
Zhetysu University named after I. Zhansugurov in Taldykorgan (Kazakhstan), in collaboration with the Islamic Organization for Food Security (IOFS), held the "2nd Central Asian Wheat Genetics and Genomics Workshop" on June 24-25, 2024, aimed at breeders and geneticists.
The Research Institute of Biotechnology and Ecology, consisting of four laboratories, including the «Molecular Genetics and Genomics» Laboratory, provided its platform for the seminar. The goal of the seminar was to develop resilient and high-quality wheat varieties to enhance food security and promote sustainable agriculture in Central Asia.
The seminar topics included pre-breeding for resilient crops, wheat variety improvement, hybrid wheat, speed breeding, molecular breeding, and KASP genotyping. Participants representing seven Kazakhstani research institutes and universities engaged with international experts from Pakistan and Turkey, including the director of IOFS, renowned wheat breeders.
EVENTS
Title: The study of genetic control of adaptation and productivity of wheat
Goal: The study of genes controlling plant height as a component of adaptation and wheat yieldTitle: “2023 Workshop on Wheat Genetics and Genomics in Central Asia”, January 30th – February 02nd 2023, Zhetysu University, Taldykorgan.
Aim: The workshop is aimed at showcasing how to use genetic and genomic methods that support modern wheat improvement and breeding. The course will be tailored according to the experience of participants and cover techniques such as genetic map construction, QTL mapping, GWAS, RNA seq, and navigation of bioinformatic and genomic resources.
Audience: The target participants are mid-career or junior scientists working with wheat or crops.
Funder and host: The workshop is fully funded by John Innes Centre, UK. The participant’s (mainly form Central Asian states) expenses such as travel, accommodation and meals will be covered by the organizers. The Zhetysu University named after I Zhansugurov, Kazakhstan, will host the workshop.
Organizers:
-Prof Cristobal Uauy, wheat genetics and genomics.
-Dr Luzie Wingen, statistic and bioinformatic analyses and data management in wheat genetics and genomics.
-Anna Backhaus, PhD candidate, studies the genetic architecture of wheat florets.
-Dr Kanat Yermekbayev, the host, studies the genetic control of adaptation and yield for Kazakh bread wheat.
our staff

    KANAT YERMEKBAYEV

    Head of laboratory

    +7 (708) 320 98 68
    Internal: (1174)

    kanat.yermekbayev@gmail.com

      AIGERIM BAKYROVA

      Acting senior researcher


      Internal: (1174)

      bakirova0202@gmail.com

        ZHULDYZ SARTBAYEVA

        Acting junior researcher


        Internal: (1174)

         sartbaeva98@list.ru

          ABDUAKASSOV AIBEK

          Acting junior Researcher

            +7 777 122 03 01
          Internal: (1174)

          aibek.abduakas@mail.ru  aibek.abduakas@gmail.com

            SHOKEN MADI

            Acting junior Researcher


            Internal: (1174)

            madi.shoken.04@mail.ru